Mysterious Infection
In 1994, a mysterious bacterial infection struck
hundreds of asthmatics throughout the U.S.; over 100
people died. The reason was finally discovered: they had
all used the same albuterol inhalant. Although the
manufacturer’s albuterol tank had been properly
disinfected, they found a particular species of bacteria,
Pseudomonas aeruginosa, freely floating in it.
Pseudomonas is notorious for forming biofilms --
clumps of sticky slime which house bacteria -- that
resist chemical disinfectants as well as the immune
system and antibiotics. |
Resistant To Disinfection
The deadly outbreak spawned over 50 court claims.
The plantiffs called in William Costerton, the director of
the Center for Biofilm Engineering at Montana State
University in Bozeman and one of the few experts on
biofilms, who testified that asthmatics breathing in
pieces of biofilm from the contaminated inhalant would
easily become infected with Pseudomonas, which
commonly causes pneumonia. For anyone unfortunate enough to breathe in a biofilm, the biofilm bacteria have
almost a 100% chance of survival in the lungs.
It was not the first time biofilms had a spotlight in high-profile cases. Costerton has testified in court about the
presence of biofilms causing problems elsewhere, for example,
on intrauterine devices (IUDs).
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99% of Bacteria Make Biofilms
These court cases highlight the widening gap in how researchers
generally view the microbial world. Microbiologists have
traditionally researched only free-floating, individual bacteria
growing in laboratory cultures.
But in the real world, 99% of all
microbial activity is in an open ecosystem using biofilms. In the
natural world and in your body, most bacteria aggregate within
big clumps of biofilms in which they behave very differently than
single, isolated bacteria. “Microbiologists have been barking up
the wrong tree since the time of Pasteur,” says Costerton.
Biofilms: They’re Everywhere!
Biofilms, once considered odd curiosities, are now one of the
hottest topics in microbiology. Biofilms occur everywhere:
dental plaque is one the most common biofilms that decay teeth,
other biofilms can clog water pipes, others can contaminate
almost any medical device inserted into the body, ranging from
contact lenses to catheters and artificial hearts. Anerobic bacteria
in biofilms can reduce sulfur to hydrogen sulfide and burn holes
in pipes. Aerobic bacteria can corrode metals by oxidation.
On computer chips, biofilms can serve as conductors and
interfere with electronic signals. “I have called biofilm-induced
corrosion the veneral disease of industry,” says biofilm pioneer
David C. White, executive director of the Center for
Environmental Biotechnology at the University of Tennessee in
Knoxville.
Their Own Little World
The renegade bacteria in biofilms bind together in a sticky web of tangled polysaccharide fibers. The biofilms, with their
bacterial nests, connect across cells with sticky strands and
anchor them to other surfaces. Within this microcosm, both
anerobic and aerobic bacteria can thrive side by side, sharing
water and nutrient passageways.
Like a circulatory system,
water flows in convective patterns through the channels which
deliver nutrients and eliminate waste. Some microbes release
hydrogen while others ingest it in order to reduce CO2 to methane.
Still others dine on dead cells.
Within their little biofilm cities, the bacteria can thrive and
multiply without harm. The sticky polysaccharide coat of the
biofilm is “like a coat of armor,” says White, which allows
different types of bacteria to “collaborate to make themselves
more powerful.”
The Biofilm Colony
By 1990, researchers confirmed that biofilm bacteria are
morphologically and metabolically distinct from free-floating
bacteria.
So what we studied in school is not how bacteria really
work. Any bacterium can form a biofilm once it is able to find a
surface to stick. Slamming up against a hard surface sets off a
genetic cascade in the bacteria that turns on specific genes to
make sticky polysaccharides and other substances to establish
the biofilm colony. Even bacteria that have been floating for a long
time in a test tube will stick somewhere, if given the chance. |
White Cell Attack
Biofilms are huge blobs compared to small white cells. White
blood cells typically are about 15 micrometers in diameter. They
can track down and engulf free-floating bacteria of one
micrometer or so, but white cells choke on biofilms which can
reach up to 100 micrometers in diameter. Some bacteria are
better than others at forming biofilms. When biofilm aggregates
are large enough, they can congest organs, glands, and air and
blood passageways; ultimately they can kill humans.
The biofilms protect the bacteria from antibiotics. “The
resistance of these biofilms to antibiotics is phenomenal,” says
Costerton, although researchers are unsure why. Preliminary
evidence suggests that different bacteria within a biofilm can
trade genes -- possibly including genes for antibiotic resistance.
But antibiotics are becoming outdated as fast as companies can
make them (with more and more microbes are becoming
antiobiotic resistant daily). A new, more effective and nontoxic
approach is needed.
Revolutionary Biofilm Dissolvers
Researchers are finding new creative ways to dissolve biofilms
in order to get at and then kill the bacteria inside. Many Super Nutrients such as turmeric, neem oil, reishi and many more can readily dissolve the biofilms. Clinical experience has
shown that they can help clear many types of infection,
including tooth-related problems. Super Nutrients can help clear
infections found in the gums, parotids, lymphatic chains in the
neck, thyroid, stomach and intestines.
First things first. Before undergoing detoxification with Super Nutrients, be sure you have good mineral balance first. Good
mineral balance is reflected by a first morning urine pH between 6.4 to 7.0. If your pH is very acid (below 6.0), work on
establishing better mineral balance by taking appropriate amounts
of highly ionized coral minerals from Japan along with a good
vitamin D source (such as U.S.P. grade cod liver oil or mycelial
extracts of medicinal mushrooms rich in pro-vitamin D).
Remarkable Results
One well-known clinical nutritionist has seen many beneficial
results using Super Nutrient biofilm busters in his clinical practice. For example,
the chronic tooth pain of one person quickly cleared with neem oil applied locally to the tooth. Much chronic
tooth pain or sensitivity is often due to underlying infection.
He has also seen great
results with external application. When essential oils such as orange essential oil is massaged into the neck area,
he often finds an immediate loosening of tight muscles with an
immediate increase in range of motion.
Breaking down biofilms with Super Nutrients so the
bacteria inside can be easily killed, may be one of the greatest
health discoveries of this century.
Potera, C., “Biofilms Invade Microbiology,” Science, Vol. 273, Sept 27.,
1996.
See IEDP Web page for more information on biofilms: Resource library,
Biofilm Systems Training Lab, etc.: http://www.erc.montana.edu/
frmain.htm |